Regulation of multimers via truncated isoforms: a novel mechanism to control nitric-oxide signaling

Nitric oxide (NO) is an essential regulator of Drosophila development and physiology. We describe a novel mode of regulation of NO synthase (NOS) function that uses endogenously produced truncated protein isoforms of Drosophila NOS (DNOS). These isoforms inhibit NOS enzymatic activity in vitro and i...

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Main Authors: Stasiv, Yuri, Kuzin, Boris, Regulski, Michael, Tully, Tim, Enikolopov, Grigori
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2004
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC517402/
https://ncbi.nlm.nih.gov/pubmed/15256486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.298004
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