Regulation of multimers via truncated isoforms: a novel mechanism to control nitric-oxide signaling

Nitric oxide (NO) is an essential regulator of Drosophila development and physiology. We describe a novel mode of regulation of NO synthase (NOS) function that uses endogenously produced truncated protein isoforms of Drosophila NOS (DNOS). These isoforms inhibit NOS enzymatic activity in vitro and i...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Stasiv, Yuri, Kuzin, Boris, Regulski, Michael, Tully, Tim, Enikolopov, Grigori
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2004
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517402/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15256486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.298004
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