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Complement protein C1q enhances macrophage foam cell survival and efferocytosis()
In the atherosclerotic lesion, macrophages ingest high levels of damaged, modified, low density lipoproteins (LDL), generating macrophage foam cells. Foam cells undergo apoptosis, and if not efficiently cleared by efferocytosis, can undergo secondary necrosis, leading to plaque instability and ruptu...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173410/ https://ncbi.nlm.nih.gov/pubmed/27895181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601445 |
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