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Complement protein C1q enhances macrophage foam cell survival and efferocytosis()
In the atherosclerotic lesion, macrophages ingest high levels of damaged, modified, low density lipoproteins (LDL), generating macrophage foam cells. Foam cells undergo apoptosis, and if not efficiently cleared by efferocytosis, can undergo secondary necrosis, leading to plaque instability and ruptu...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173410/ https://ncbi.nlm.nih.gov/pubmed/27895181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601445 |
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