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Self-Organizing Global Gene Expression Regulated through Criticality: Mechanism of the Cell-Fate Change

BACKGROUND: A fundamental issue in bioscience is to understand the mechanism that underlies the dynamic control of genome-wide expression through the complex temporal-spatial self-organization of the genome to regulate the change in cell fate. We address this issue by elucidating a physically motiva...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tsuchiya, Masa, Giuliani, Alessandro, Hashimoto, Midori, Erenpreisa, Jekaterina, Yoshikawa, Kenichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173342/
https://ncbi.nlm.nih.gov/pubmed/27997556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167912
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