Mice deficient in the Vici syndrome gene Epg5 exhibit features of retinitis pigmentosa

Autophagy helps to maintain cellular homeostasis by removing misfolded proteins and damaged organelles, and generally acts as a cytoprotective mechanism for neuronal survival. Here we showed that mice deficient in the Vici syndrome gene Epg5, which is required for autophagosome maturation, show accu...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Miao, Guangyan, Zhao, Yan G., Zhao, Hongyu, Ji, Cuicui, Sun, Huayu, Chen, Yingyu, Zhang, Hong
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Basic Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173265/
https://ncbi.nlm.nih.gov/pubmed/27715390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238554
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