Effective Respiratory CD8 T-Cell Immunity to Influenza Virus Induced by Intranasal Carbomer-Lecithin-Adjuvanted Non-replicating Vaccines

CD8(+) cytotoxic T lymphocytes (CTLs) are critical for clearing many viral infections, and protective CTL memory can be induced by vaccination with attenuated viruses and vectors. Non-replicating vaccines are typically potentiated by the addition of adjuvants that enhance humoral responses, however...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Gasper, David J., Neldner, Brandon, Plisch, Erin H., Rustom, Hani, Carrow, Emily, Imai, Hirotaka, Kawaoka, Yoshihiro, Suresh, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173246/
https://ncbi.nlm.nih.gov/pubmed/27997610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006064
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