Direct cell fate conversion of human somatic stem cells into cone and rod photoreceptor-like cells by inhibition of microRNA-203

Stem cell-based photoreceptor differentiation strategies have been the recent focus of therapies for retinal degenerative diseases. Previous studies utilized embryonic stem (ES) cells and neural retina differentiation cocktails, including DKK1 and Noggin. Here, we show a novel microRNA-mediated stra...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Choi, Soon Won, Shin, Ji-Hee, Kim, Jae-Jun, Shin, Tae-Hoon, Seo, Yoojin, Kim, Hyung-Sik, Kang, Kyung-Sun
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173122/
https://ncbi.nlm.nih.gov/pubmed/27283900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9882
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