Luminal STAT5 mediates H2AX promoter activity in distinct population of basal mammary epithelial cells

Deregulated STAT5 activity in the mammary gland causes parity-dependent tumorigenesis. Epithelial cell cultures transfected with constitutively active STAT5 express higher levels of the histone H2AX than their non-transfected counterparts. Higher H2AX expression may be involved in tumorigenesis. Her...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Reichenstein, Moshe, Rauner, Gat, Kfir, Shenhav, Kisliouk, Tatiana, Barash, Itamar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173096/
https://ncbi.nlm.nih.gov/pubmed/27260000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9718
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