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Luminal STAT5 mediates H2AX promoter activity in distinct population of basal mammary epithelial cells
Deregulated STAT5 activity in the mammary gland causes parity-dependent tumorigenesis. Epithelial cell cultures transfected with constitutively active STAT5 express higher levels of the histone H2AX than their non-transfected counterparts. Higher H2AX expression may be involved in tumorigenesis. Her...
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| Publicado en: | Oncotarget |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173096/ https://ncbi.nlm.nih.gov/pubmed/27260000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9718 |
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