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Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia

T cell acute lymphoblastic leukemia (T-ALL) develops through accumulation of multiple genomic alterations within T-cell progenitors resulting in clonal heterogeneity among leukemic cells. Human T-ALL xeno-transplantation in immunodeficient mice is a gold standard approach to study leukemia biology a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Poglio, Sandrine, Lewandowski, Daniel, Calvo, Julien, Caye, Aurélie, Gros, Audrey, Laharanne, Elodie, Leblanc, Thierry, Landman-Parker, Judith, Baruchel, André, Soulier, Jean, Ballerini, Paola, Clappier, Emmanuelle, Pflumio, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173081/
https://ncbi.nlm.nih.gov/pubmed/27191650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9313
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