Mitochondrial GRIM-19 as a potential therapeutic target for STAT3-dependent carcinogenesis of gastric cancer

Aberrant STAT3 activation occurs in most human gastric cancers (GCs) and contributes to the malignant progression of GC, but mechanism(s) underlying aberrant STAT3 remain largely unknown. Here we demonstrated that the gene associated with retinoid interferon-induced mortality 19 (GRIM-19) was severe...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Huang, Yi, Yang, Meihua, Hu, Huajian, Zhao, Xiaodong, Bao, Liming, Huang, Daochao, Song, Lihua, Li, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173068/
https://ncbi.nlm.nih.gov/pubmed/27167343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9167
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