microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway

microRNA-374a (miR-374a) exhibits oncogenic functions in various tumor types. Here we report that miR-374a suppresses proliferation, invasion, migration and intrahepatic metastasis in colon adenocarcinoma cell lines HCT116 and SW620. Notably, we detected that PI3K/AKT signaling and its downstream ce...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Chen, Yiyu, Jiang, Jingwen, Zhao, Mengyang, Luo, Xiaojun, Liang, Zixi, Zhen, Yan, Fu, Qiaofen, Deng, Xiaojie, Lin, Xian, Li, Libo, Luo, Rongcheng, Liu, Zhen, Fang, Weiyi
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173061/
https://ncbi.nlm.nih.gov/pubmed/27191497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9320
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares