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Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia
In Chronic Lymphocytic Leukemia (CLL), infiltration of lymph nodes by leukemic cells is observed in patients with progressive disease and adverse outcome. We have previously demonstrated that B-cell receptor (BCR) engagement resulted in CXCR4 down-regulation in CLL cells, correlating with a shorter...
Zapisane w:
Wydane w: | Oncotarget |
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Główni autorzy: | , , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Impact Journals LLC
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173040/ https://ncbi.nlm.nih.gov/pubmed/27127886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9031 |
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