Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia

In Chronic Lymphocytic Leukemia (CLL), infiltration of lymph nodes by leukemic cells is observed in patients with progressive disease and adverse outcome. We have previously demonstrated that B-cell receptor (BCR) engagement resulted in CXCR4 down-regulation in CLL cells, correlating with a shorter...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Oncotarget
Κύριοι συγγραφείς: Saint-Georges, Stéphane, Quettier, Maude, Bouyaba, Marouane, Le Coquil, Stéphanie, Laurienté, Vanessa, Guittat, Lionel, Lévy, Vincent, Ajchenbaum-Cymbalista, Florence, Varin-Blank, Nadine, Le Roy, Christine, Ledoux, Dominique
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2016
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173040/
https://ncbi.nlm.nih.gov/pubmed/27127886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9031
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