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Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains.

Mice homozygous for the viable Sl allele steel-Dickie (Sld) are sterile, severely anemic, and black-eyed white. The nature of the Sld mutation was investigated at the molecular level and was found to be due to a 4.0-kilobase intragenic deletion in mast cell growth factor (MGF) genomic sequences, pro...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Brannan, C I, Lyman, S D, Williams, D E, Eisenman, J, Anderson, D M, Cosman, D, Bedell, M A, Jenkins, N A, Copeland, N G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51727/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1711207/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.11.4671
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