Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains.
Mice homozygous for the viable Sl allele steel-Dickie (Sld) are sterile, severely anemic, and black-eyed white. The nature of the Sld mutation was investigated at the molecular level and was found to be due to a 4.0-kilobase intragenic deletion in mast cell growth factor (MGF) genomic sequences, pro...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1991
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1711207/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.11.4671 |
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