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Kinetics of antigenic peptide binding to the class II major histocompatibility molecule I-Ad.

Using high-performance size-exclusion chromatography and fluorescence spectroscopy, we investigated the kinetics of fluorescent peptide reactions with detergent-solubilized I-Ad, a class II molecule of the mouse major histocompatibility complex. At pH 7.0 and 37 degrees C the half-time for the bindi...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Tampé, R, McConnell, H M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1991
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2052549/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.11.4661
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