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Improvement of gamete quality by stimulating and feeding the endogenous antioxidant system: mechanisms, clinical results, insights on gene-environment interactions and the role of diet

Oxidative damage triggers extensive repair in gametes and thereafter in the zygote but it results in clinically relevant damage when affecting the maturation of the gametes chromatin, i.e. padlocking and epigenetic marking. It associates with defective DNA methylation and/or with oxidation of the me...

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Detalhes bibliográficos
Publicado no:J Assist Reprod Genet
Main Authors: Dattilo, Maurizio, Giuseppe, D’Amato, Ettore, Caroppo, Ménézo, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171888/
https://ncbi.nlm.nih.gov/pubmed/27423667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-016-0767-4
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