Evolution of multiple cell clones over a 29-year period of a CLL patient

Chronic lymphocytic leukaemia (CLL) is a frequent B-cell malignancy, characterized by recurrent somatic chromosome alterations and a low level of point mutations. Here we present single-nucleotide polymorphism microarray analyses of a single CLL patient over 29 years of observation and treatment, an...

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發表在:Nat Commun
Main Authors: Zhao, Zhikun, Goldin, Lynn, Liu, Shiping, Wu, Liang, Zhou, Weiyin, Lou, Hong, Yu, Qichao, Tsang, Shirley X., Jiang, Miaomiao, Li, Fuqiang, McMaster, MaryLou, Li, Yang, Lin, Xinxin, Wang, Zhifeng, Xu, Liqin, Marti, Gerald, Li, Guibo, Wu, Kui, Yeager, Meredith, Yang, Huanming, Xu, Xun, Chanock, Stephen J., Li, Bo, Hou, Yong, Caporaso, Neil, Dean, Michael
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171825/
https://ncbi.nlm.nih.gov/pubmed/27982015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13765
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