Ribavirin suppresses bacterial virulence by targeting LysR-type transcriptional regulators

Targeting bacterial virulence mechanisms without compromising bacterial growth is a promising strategy to prevent drug resistance. LysR-type transcriptional regulators (LTTRs) possess structural conservation across bacterial species and regulate virulence in numerous pathogens, making them attractiv...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mandal, Rahul Shubhra, Ta, Atri, Sinha, Ritam, Theeya, Nagaraja, Ghosh, Anirban, Tasneem, Mohsina, Bhunia, Anirban, Koley, Hemanta, Das, Santasabuj
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171790/
https://ncbi.nlm.nih.gov/pubmed/27991578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39454
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