Using anti-poly(ethylene glycol) bioparticles for the quantitation of PEGylated nanoparticles

Attachment of polyethylene glycol (PEG) molecules to nanoparticles (PEGylation) is a widely-used method to improve the stability, biocompatibility and half-life of nanomedicines. However, the evaluation of the PEGylated nanomedicine pharmacokinetics (PK) requires the decomposition of particles and p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hsieh, Yuan-Chin, Cheng, Ta-Chun, Wang, Hsin-Ell, Li, Jia-Je, Lin, Wen-Wei, Huang, Chien-Chiao, Chuang, Chih-Hung, Wang, Yeng-Tseng, Wang, Jaw-Yuan, Roffler, Steve R., Chuang, Kuo-Hsiang, Cheng, Tian-Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171718/
https://ncbi.nlm.nih.gov/pubmed/27991598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39119
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