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Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation

Dendritic cells (DCs) have been implicated in the pathogenesis of psoriasis but the roles for specific DC subsets are not well defined. Here we show that DCs are required for psoriasis-like changes in mouse skin induced by the local injection of IL-23. However, Flt3L-dependent DCs and resident Lange...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Singh, Tej Pratap, Zhang, Howard H., Borek, Izabela, Wolf, Peter, Hedrick, Michael N., Singh, Satya P., Kelsall, Brian L., Clausen, Bjorn E., Farber, Joshua M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171657/
https://ncbi.nlm.nih.gov/pubmed/27982014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13581
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