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Daily leptin blunts marrow fat but does not impact bone mass in calorie restricted mice

Starvation induces low bone mass and high bone marrow adiposity in humans, but the underlying mechanisms are poorly understood. The adipokine leptin falls in starvation, suggesting hypoleptinemia may be a link between negative energy balance, bone marrow fat accumulation and impaired skeletal acquis...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: DEVLIN, MJ, BROOKS, DJ, CONLON, C, VAN VLIET, M, LOUIS, L, ROSEN, CJ, BOUXSEIN, ML
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171226/
https://ncbi.nlm.nih.gov/pubmed/27340200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-15-0473
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