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Divergent Synthesis and Real-Time Biological Annotation of Optically Active Tetrahydrocyclopenta[c]pyranone Derivatives

[Image: see text] Sp(3)-rich compounds are underrepresented in libraries for probe- and drug-discovery, despite their promise of extending the range of accessible molecular shapes beyond planar geometries. With this in mind, a collection of single-enantiomer bicyclic, fused cyclopentenones underpinn...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Nelson, Shawn D., Wawer, Mathias J., Schreiber, Stuart L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171204/
https://ncbi.nlm.nih.gov/pubmed/27978655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b03118
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