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Being “penny-wise but pound foolish” in cancer immunotherapy research: the urgent need for mouse cancer models to reflect human modifying factors

Inbred mice are the mainstay for preclinical cancer assessment of potential therapeutics, especially immune-based approaches. However, the use of young, lean, inbred mice housed under specific-pathogen-free conditions does not mirror the human cancer scenario. This commentary discusses some of the i...

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Bibliografiska uppgifter
I publikationen:J Immunother Cancer
Huvudupphovsman: Murphy, William J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5170894/
https://ncbi.nlm.nih.gov/pubmed/28031818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-016-0195-0
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