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Nuclear envelope rupture drives genome instability in cancer

The nuclear envelope, composed of two lipid bilayers and numerous accessory proteins, has evolved to house the genetic material of all eukaryotic cells. In so doing, the nuclear envelope provides a physical barrier between chromosomes and the cytoplasm. Once believed to be highly stable, recent stud...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Lim, Sanghee, Quinton, Ryan J., Ganem, Neil J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5170854/
https://ncbi.nlm.nih.gov/pubmed/27799497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-02-0098
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