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Dynein-mediated trafficking negatively regulates LET-23 EGFR signaling

Epidermal growth factor receptor (EGFR) signaling is essential for animal development, and increased signaling underlies many human cancers. Identifying the genes and cellular processes that regulate EGFR signaling in vivo will help to elucidate how this pathway can become inappropriately activated....

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Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Skorobogata, Olga, Meng, Jassy, Gauthier, Kimberley, Rocheleau, Christian E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5170559/
https://ncbi.nlm.nih.gov/pubmed/27654944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-11-0757
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