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Dynein-mediated trafficking negatively regulates LET-23 EGFR signaling

Epidermal growth factor receptor (EGFR) signaling is essential for animal development, and increased signaling underlies many human cancers. Identifying the genes and cellular processes that regulate EGFR signaling in vivo will help to elucidate how this pathway can become inappropriately activated....

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Skorobogata, Olga, Meng, Jassy, Gauthier, Kimberley, Rocheleau, Christian E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5170559/
https://ncbi.nlm.nih.gov/pubmed/27654944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-11-0757
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