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What Drives Positive Selection in the Drosophila piRNA Machinery? The Genomic Autoimmunity Hypothesis

In animals, PIWI-interacting RNAs (piRNAs) play a crucial role in genome defense. Moreover, because piRNAs can be maternally transmitted, they contribute to the epigenetic profile of inheritance. Multiple studies, especially in Drosophila, have demonstrated that the machinery of piRNA biogenesis is...

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Bibliografske podrobnosti
izdano v:Yale J Biol Med
Main Authors: Blumenstiel, Justin P., Erwin, Alexandra A., Hemmer, Lucas W.
Format: Artigo
Jezik:Inglês
Izdano: YJBM 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168828/
https://ncbi.nlm.nih.gov/pubmed/28018141
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