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Circulating cell-free DNA-based epigenetic assay can detect early breast cancer

BACKGROUND: Circulating cell-free DNA (cfDNA) has recently been recognized as a resource for biomarkers of cancer progression, treatment response, and drug resistance. However, few have demonstrated the usefulness of cfDNA for early detection of cancer. Although aberrant DNA methylation in cfDNA has...

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Publicat a:Breast Cancer Res
Autors principals: Uehiro, Natsue, Sato, Fumiaki, Pu, Fengling, Tanaka, Sunao, Kawashima, Masahiro, Kawaguchi, Kosuke, Sugimoto, Masahiro, Saji, Shigehira, Toi, Masakazu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168705/
https://ncbi.nlm.nih.gov/pubmed/27993161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0788-z
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