A Novel Sortase, SrtC2, from Streptococcus pyogenes Anchors a Surface Protein Containing a QVPTGV Motif to the Cell Wall

The important human pathogen Streptococcus pyogenes (group A streptococcus GAS), requires several surface proteins to interact with its human host. Many of these are covalently linked by a sortase enzyme to the cell wall via a C-terminal LPXTG motif. This motif is followed by a hydrophobic region an...

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Vydáno v:J Bacteriol
Hlavní autoři: Barnett, Timothy C., Patel, Aman R., Scott, June R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2004
Témata:
Molecular Biology of Pathogens
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516832/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15317792/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.17.5865-5875.2004
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