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A Novel Sortase, SrtC2, from Streptococcus pyogenes Anchors a Surface Protein Containing a QVPTGV Motif to the Cell Wall

The important human pathogen Streptococcus pyogenes (group A streptococcus GAS), requires several surface proteins to interact with its human host. Many of these are covalently linked by a sortase enzyme to the cell wall via a C-terminal LPXTG motif. This motif is followed by a hydrophobic region an...

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Autori principali: Barnett, Timothy C., Patel, Aman R., Scott, June R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC516832/
https://ncbi.nlm.nih.gov/pubmed/15317792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.17.5865-5875.2004
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