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Amyloid-beta Induces Sleep Fragmentation that is Rescued by Fatty Acid Binding Proteins in Drosophila

Disruption of sleep/wake activity in Alzheimer’s disease (AD) patients significantly affects their quality of life, and that of their caretakers, and is a major contributing factor for institutionalization. Levels of amyloid-β (Aβ) have been shown to be regulated by neuronal activity and to correlat...

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Bibliographic Details
Published in:J Neurosci Res
Main Authors: Gerstner, Jason R., Lenz, Olivia, Vanderheyden, William M., Chan, May T., Pfeiffenberger, Cory, Pack, Allan I.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167666/
https://ncbi.nlm.nih.gov/pubmed/27320125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23778
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