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New developments in the genetics and pathogenesis of tumours in tuberous sclerosis complex

In just the past five years, dramatic changes have occurred in the clinical management of Tuberous Sclerosis Complex (TSC). Detailed knowledge about the role of the TSC proteins in regulating the activity of the mammalian Target of Rapamycin Complex 1 (mTORC1) underlies this paradigm-shifting progre...

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Détails bibliographiques
Publié dans:J Pathol
Auteurs principaux: Lam, Hilaire C., Nijmeh, Julie S., Henske, Elizabeth P.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167646/
https://ncbi.nlm.nih.gov/pubmed/27753446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4827
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