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Early Embryonic Death in Mice Lacking the β-Catenin-Binding Protein Duplin
The Wnt signaling pathway plays a pivotal role in vertebrate early development and morphogenesis. Duplin (axis duplication inhibitor) interacts with β-catenin and prevents its binding to Tcf, thereby inhibiting downstream Wnt signaling. Here we show that Duplin is expressed predominantly from early-...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516734/ https://ncbi.nlm.nih.gov/pubmed/15367660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8386-8394.2004 |
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