Phase I/II Trial of Sorafenib in Combination with Vinorelbine as First-Line Chemotherapy for Metastatic Breast Cancer

BACKGROUND: Preclinical models have reported a synergistic interaction between sorafenib and vinorelbine. We investigated the toxicity, efficacy, and pharmacokinetics interaction of this combination as first-line treatment for patients with metastatic breast cancer. METHODS: Patients were HER2-negat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ferrario, Cristiano, Strepponi, Ivan, Esfahani, Khashayar, Charamis, Helen, Langleben, Adrian, Scarpi, Emanuela, Nanni, Oriana, Miller, Wilson H., Panasci, Lawrence C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167316/
https://ncbi.nlm.nih.gov/pubmed/27992451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167906
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