Urinary Measurement of Epigenetic DNA Modifications: A Non‐Invasive Assessment of the Whole‐Body Epigenetic Status in Healthy Subjects and Colorectal Cancer Patients

Active mechanism of DNA demethylation can be responsible for the activation of previously silenced genes. Products of 5‐methylcytosine oxidation are released into the bloodstream and eventually excreted with urine. Therefore, whole‐body epigenetic status can be assessed non‐invasively on the basis o...

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Publicat a:ChemistryOpen
Autors principals: Rozalski, Rafal, Gackowski, Daniel, Siomek‐Gorecka, Agnieszka, Banaszkiewicz, Zbigniew, Olinski, Ryszard
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167278/
https://ncbi.nlm.nih.gov/pubmed/28032024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600103
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