Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs

Caveolae are invaginated plasma membrane domains involved in mechanosensing, signaling, endocytosis, and membrane homeostasis. Oligomers of membrane-embedded caveolins and peripherally attached cavins form the caveolar coat whose structure has remained elusive. Here, purified Cavin1 60S complexes we...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Stoeber, Miriam, Schellenberger, Pascale, Siebert, C. Alistair, Leyrat, Cedric, Helenius, Ari, Grünewald, Kay
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167190/
https://ncbi.nlm.nih.gov/pubmed/27834731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616838113
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