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4‐Aminopyridine promotes functional recovery and remyelination in acute peripheral nerve injury

Traumatic peripheral nerve damage is a major medical problem without effective treatment options. In repurposing studies on 4‐aminopyridine (4‐AP), a potassium channel blocker that provides symptomatic relief in some chronic neurological afflictions, we discovered this agent offers significant promi...

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Dades bibliogràfiques
Publicat a:EMBO Mol Med
Autors principals: Tseng, Kuang‐Ching, Li, Haiyan, Clark, Andrew, Sundem, Leigh, Zuscik, Michael, Noble, Mark, Elfar, John
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167128/
https://ncbi.nlm.nih.gov/pubmed/27861125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201506035
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