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Comparison of toxicogenomic responses to phthalate ester exposure in an organotypic testis co-culture model and responses observed in vivo

We have developed a three-dimensional testicular co-culture system (3D-TCS) which mimics in vivo testes. In this study, transcriptomic responses to phthalate esters (PE’s) were compared in the 3D-TCS with responses in rat testes in vivo. Microarray data from the 3D-TCS and from in vivo testes were u...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Reprod Toxicol
Päätekijät: Harris, Sean, Hermsen, Sanne A.B., Yu, Xiaozhong, Hong, Sung Woo, Faustman, Elaine M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166712/
https://ncbi.nlm.nih.gov/pubmed/26472102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2015.10.002
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