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Crystal Growth Inhibitors for the Prevention of L-Cystine Kidney Stones through Molecular Design

Crystallization of L-cystine is a critical process in the pathogenesis of kidney stone formation in cystinuria, a disorder affecting at least 20,000 U.S. citizens. Current therapeutic treatments for this disease are somewhat effective but often lead to adverse side effects. Real-time in situ atomic...

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發表在:Science
Main Authors: Rimer, Jeffrey D., An, Zhihua, Zhu, Zina, Lee, Michael H., Goldfarb, David S., Wesson, Jeffrey A., Ward, Michael D.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166609/
https://ncbi.nlm.nih.gov/pubmed/20947757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191968
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