Functional Deficits Precede Structural Lesions in Mice With High-Fat Diet–Induced Diabetic Retinopathy

Obesity predisposes to human type 2 diabetes, the most common cause of diabetic retinopathy. To determine if high-fat diet–induced diabetes in mice can model retinal disease, we weaned mice to chow or a high-fat diet and tested the hypothesis that diet-induced metabolic disease promotes retinopathy....

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Rajagopal, Rithwick, Bligard, Gregory W., Zhang, Sheng, Yin, Li, Lukasiewicz, Peter, Semenkovich, Clay F.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2016
Fag:
Complications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166563/
https://ncbi.nlm.nih.gov/pubmed/26740595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1255
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