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β-Arrestin 1-dependent regulation of Rap2 is required for fMLP-stimulated chemotaxis in neutrophil-like HL-60 cells

β-Arrestins have emerged as key regulators of cytoskeletal rearrangement that are required for directed cell migration. Whereas it is known that β-arrestins are required for formyl-Met-Leu-Phe receptor (FPR) recycling, less is known about their role in regulating FPR-mediated neutrophil chemotaxis....

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Bibliographische Detailangaben
Veröffentlicht in:J Leukoc Biol
Hauptverfasser: Gera, Nidhi, Swanson, Kenneth D., Jin, Tian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Leukocyte Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166435/
https://ncbi.nlm.nih.gov/pubmed/27493245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A1215-572R
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