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Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1

Enteropathogenic Escherichia coli delivers a subset of effectors into host cells via a type III secretion system, and this step is required for the progression of disease. Here, we show that the type III effectors, EspG and its homolog Orf3, trigger actin stress fiber formation and the destruction o...

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Autors principals: Matsuzawa, Takeshi, Kuwae, Asaomi, Yoshida, Sei, Sasakawa, Chihiro, Abe, Akio
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516631/
https://ncbi.nlm.nih.gov/pubmed/15318166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600359
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