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Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides.

Studies in hepatitis B e antigen (HBeAg)-expressing transgenic mice indicate that self tolerance to two T-cell determinants on the same transgenic self molecule can differ markedly. The dominant T-cell site on HBeAg is tolerogenic, whereas a proportion of T cells recognizing a second T-cell site eva...

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Detalhes bibliográficos
Main Authors: Milich, D R, McLachlan, A, Raney, A K, Houghten, R, Thornton, G B, Maruyama, T, Hughes, J L, Jones, J E
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51656/
https://ncbi.nlm.nih.gov/pubmed/1827917
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