Proendocrine genes coordinate the pancreatic islet differentiation program in vitro

In the developing pancreas, the basic helix–loop–helix (bHLH) protein Neurogenin3 (Ngn3) specifies which precursor cells ultimately will become endocrine cells and initiates the islet differentiation program. NeuroD1, a closely related bHLH protein and a downstream target of Ngn3, maintains the diff...

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Autors principals: Gasa, Rosa, Mrejen, Caroline, Leachman, Nathaniel, Otten, Marc, Barnes, Michael, Wang, Juehu, Chakrabarti, Swarup, Mirmira, Raghavendra, German, Michael
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516555/
https://ncbi.nlm.nih.gov/pubmed/15340143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405301101
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