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Proendocrine genes coordinate the pancreatic islet differentiation program in vitro
In the developing pancreas, the basic helix–loop–helix (bHLH) protein Neurogenin3 (Ngn3) specifies which precursor cells ultimately will become endocrine cells and initiates the islet differentiation program. NeuroD1, a closely related bHLH protein and a downstream target of Ngn3, maintains the diff...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516555/ https://ncbi.nlm.nih.gov/pubmed/15340143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405301101 |
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