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Accelerated folding in the weak hydrophobic environment of a chaperonin cavity: Creation of an alternate fast folding pathway

Recent experiments suggest that the folding of certain proteins can take place entirely within a chaperonin-like cavity. These substrate proteins experience folding rate enhancements without undergoing multiple rounds of ATP-induced binding and release from the chaperonin. Rather, they undergo only...

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Hlavní autoři: Jewett, A. I., Baumketner, A., Shea, J.-E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC516546/
https://ncbi.nlm.nih.gov/pubmed/15331776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400720101
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