Efficient Transformation of Primary Human Mesenchymal Stromal Cells by Adenovirus Early Region 1 Oncogenes

Previous observations that human amniotic fluid cells (AFC) can be transformed by human adenovirus type 5 (HAdV-5) E1A/E1B oncogenes prompted us to identify the target cells in the AFC population that are susceptible to transformation. Our results demonstrate that one cell type corresponding to mese...

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Publicat a:J Virol
Autors principals: Speiseder, Thomas, Hofmann-Sieber, Helga, Rodríguez, Estefanía, Schellenberg, Anna, Akyüz, Nuray, Dierlamm, Judith, Spruss, Thilo, Lange, Claudia, Dobner, Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Transformation and Oncogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165183/
https://ncbi.nlm.nih.gov/pubmed/27795433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01782-16
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