Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein

Given the dual role of CD4 T cells as both immune effectors and targets for HIV infection, the balance of CD4 versus CD8 T cell-mediated responses induced by candidate AIDS vaccines may be critical in determining postvaccination infection outcomes. An attenuated recombinant varicella-zoster virus va...

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Hlavní autoři: Staprans, Silvija I., Barry, Ashley P., Silvestri, Guido, Safrit, Jeffrey T., Kozyr, Natalia, Sumpter, Beth, Nguyen, Hanh, McClure, Harold, Montefiori, David, Cohen, Jeffrey I., Feinberg, Mark B.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC516468/
https://ncbi.nlm.nih.gov/pubmed/15326293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404739101
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