Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-κB and proinflammatory gene program activation in intestinal epithelial cells

BACKGROUND: Infection of intestinal epithelial cells by pathogenic Salmonella leads to activation of signaling cascades that ultimately initiate the proinflammatory gene program. The transcription factor NF-κB is a key regulator/activator of this gene program and is potently activated. We explored t...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Tallant, Thomas, Deb, Amitabha, Kar, Niladri, Lupica, Joseph, de Veer, Michael J, DiDonato, Joseph A
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15324458/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2180-4-33
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