Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Up-Regulates Transcription of Human Telomerase Reverse Transcriptase Promoter through Interaction with Transcription Factor Sp1

Telomerase is required for the maintenance of telomere length and is an important determinant for cell immortalization. In human cells, telomerase activity is due to the expression of its enzymatic subunit, human telomerase reverse transcriptase (hTERT). The expression of hTERT is not typically dete...

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Hlavní autoři: Verma, Subhash C., Borah, Sumit, Robertson, Erle S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC516419/
https://ncbi.nlm.nih.gov/pubmed/15367601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10348-10359.2004
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