Short Interfering RNA-Mediated Inhibition of Herpes Simplex Virus Type 1 Gene Expression and Function during Infection of Human Keratinocytes

RNA interference (RNAi) is an antiviral mechanism that is activated when double-stranded RNA is cleaved into fragments, called short interfering RNA (siRNA), that prime an inducible gene silencing enzyme complex. We applied RNAi against a herpes simplex virus type 1 (HSV-1) gene, glycoprotein E, whi...

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Detalhes bibliográficos
Main Authors: Bhuyan, Prakash K., Karikò, Katalin, Capodici, John, Lubinski, John, Hook, Lauren M., Friedman, Harvey M., Weissman, Drew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516413/
https://ncbi.nlm.nih.gov/pubmed/15367593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10276-10281.2004
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