Temporal Modulation of an Autoprotease Is Crucial for Replication and Pathogenicity of an RNA Virus

Pestiviruses belong to the family Flaviviridae, and their genome is a single-stranded RNA of positive polarity encoding one large polyprotein which is further processed into mature proteins. Noncytopathogenic (noncp) strains of the pestivirus bovine viral diarrhea virus (BVDV) can establish persiste...

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Detalhes bibliográficos
Main Authors: Lackner, T., Müller, A., Pankraz, A., Becher, P., Thiel, H.-J., Gorbalenya, A. E., Tautz, N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516412/
https://ncbi.nlm.nih.gov/pubmed/15367643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10765-10775.2004
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