Dual Role of Prostratin in Inhibition of Infection and Reactivation of Human Immunodeficiency Virus from Latency in Primary Blood Lymphocytes and Lymphoid Tissue

To design strategies to purge latent reservoirs of human immunodeficiency virus type 1 (HIV-1), we investigated mechanisms by which a non-tumor-promoting phorbol ester, prostratin, inhibits infection of CD4(+) T lymphocytes and at the same time reactivates virus from latency. CD4(+) T lymphocytes fr...

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Detalhes bibliográficos
Main Authors: Biancotto, Angélique, Grivel, Jean-Charles, Gondois-Rey, Françoise, Bettendroffer, Lise, Vigne, Robert, Brown, Stephen, Margolis, Leonid B., Hirsch, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516376/
https://ncbi.nlm.nih.gov/pubmed/15367617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10507-10515.2004
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